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Simple surgery prevents strokes in heart patients
on May 15, 2021 at 1:10 pm
The study tracked 4,811 people in 27 countries who are living with atrial fibrillation and taking blood thinners. Consenting patients undertaking cardiopulmonary bypass surgery were randomly selected for the additional left atrial appendage occlusion surgery; their outcomes compared with those who only took medicine. They were all followed for a median of four years. […]
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Study of 70,000 individuals links dementia to smoking and cardiovascular disease
on May 13, 2021 at 7:48 pm
In the largest study of the associations between smoking and cardiovascular disease on cognitive function, researchers found both impair the ability to learn and memorize; and that the effects of smoking are more pronounced among females, while males are more impaired by cardiovascular disease. […]
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Obesity during adolescence linked to increased risk of stroke as an adult, study finds
on May 13, 2021 at 12:50 pm
Higher body mass index (BMI) -- an indicator of obesity -- in late adolescence is associated with a significantly higher risk of first ischemic stroke in men and women under age 50, regardless of whether they had Type 2 diabetes, a new study finds. Even BMIs in the high-normal range are associated with increased stroke risk in both men and women. […]
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An anesthetic may affect tau spread in the brain to promote Alzheimer's disease pathology
on May 12, 2021 at 3:56 pm
Previous research has suggested that an inhaled anesthetic called sevoflurane may promote the brain changes of Alzheimer's disease. A new study in cells and mice reveals that sevoflurane causes the Alzheimer's-related protein tau to leave neurons and enter immune cells (microglia) in the brain, ultimately leading to inflammation and cognitive impairment. […]
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Controlling cholesterol in microglia alleviates chronic pain, opioid-free
on May 10, 2021 at 11:25 pm
Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment. Researchers have used a mouse model to demonstrate the pivotal role of cholesterol in CIPN, and proposed a novel therapeutic approach to reverse it. […]
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Thin and brittle bones strongly linked to women's heart disease risk
on May 6, 2021 at 10:33 pm
Thin and brittle bones are strongly linked to women's heart disease risk, with thinning of the lower (lumbar) spine, top of the thigh bone (femoral neck), and hip especially predictive of a heightened heart attack and stroke risk. […]
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Have high blood pressure? You may want to check your meds
on May 6, 2021 at 2:54 pm
Nearly 1 in 5 adults with high blood pressure, a leading risk factor for heart disease and stroke, also take a medicine that could be elevating their blood pressure, according to new research. The results underscore the need for patients to routinely review all of the medications they take with their care team, including those available over the counter, to make sure none could be interfering with blood pressure lowering efforts. […]
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Too much, too little sleep linked to elevated heart risks in people free from disease
on May 5, 2021 at 1:03 pm
People who clock six to seven hours of sleep a night had the lowest chance of dying from a heart attack or stroke when compared with those who got less or more sleep, according to a new study. This trend remained true even after the research team accounted for other known conditions or risk factors for heart disease or stroke. […]
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Why does heart scarring cause abnormal rhythms in some people but not others?
on May 4, 2021 at 5:57 pm
Scientists have shed light on why some people who have a stroke do not also have abnormal heart rhythms, even though their hearts contain similar scar tissue. […]
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Cancer-linked mutation accelerates growth of abnormal stroke-causing brain blood vessels
on April 28, 2021 at 3:37 pm
Researchers have discovered an explanation for why cerebral cavernous malformations (CCMs) -- clusters of dilated blood vessels in the brain -- can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene (PIK3CA) could exacerbate existing CCMs in the brain. Furthermore, repurposing an already existing anticancer drug showed promise in mouse models of CCMs in improving brain-vascular health and preventing bleeding into the brain tissue. […]
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Researchers identify protein produced after stroke that triggers neurodegeneration
on April 27, 2021 at 8:32 pm
Researchers have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke. […]
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How philosophy can change the understanding of pain
on April 23, 2021 at 1:54 pm
Researchers have investigated how philosophical approaches can be used to think in new ways about pain and its management. The researchers advocate not merely reducing chronic pain management to searching and treating underlying physical changes but instead adopting an approach that focuses on the person as a whole. […]
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Changing views on atherosclerosis
on April 21, 2021 at 4:46 pm
Atherosclerosis -- hardening of the arteries -- is now involved in the majority of deaths worldwide, and advances in our understanding of the biology of the disease are changing traditional views and opening up new avenues for treatment. […]
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One in five American adults experience chronic pain
on April 20, 2021 at 1:29 pm
Researchers report that 50.2 million (20.5 percent) U.S. adults experience chronic pain based on analysis of the new NHIS data. They estimated the total value of lost productivity due to chronic pain to be nearly $300 billion annually. […]
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COVID-19: Tsunami of chronic health conditions expected, research and health care disrupted
on April 6, 2021 at 12:41 pm
Cardiometabolic diseases including heart disease, obesity, hypertension and type 2 diabetes, are at the crest of an impending tsunami of chronic health conditions as a result of the SARS-CoV-2 pandemic that will affect society for decades. Interventions and universal health care are recommended to focus on prevention of cardiometabolic diseases, including programs that support healthy lifestyle behaviors, blood pressure control, obesity management and tobacco cessation. […]
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